Author

C. Petosa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 2 Approach:biophysical modeling· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. B. Barlas· 1 shared A. Hamiche· 1 shared A. Le Gouellec· 1 shared A. PALENCIA· 1 shared B. A. Kashemirov· 1 shared B. Ozden· 1 shared C. E. McKenna· 1 shared C. Garnaud· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperBiophysics

A. B. Barlas

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cytosolic acetyl-CoA synthetase (ACSS2) does not generate butyryl- and crotonyl-CoA

N. Zeaiter, L. Belot, V. Cunin, R. Abi Nahed, M. Tokarska-Schlattner, A. Le Gouellec, C. Petosa, S. Khochbin, U. Schlattner

The paper shows ACSS2 does not generate butyryl- or crotonyl-CoA from SCFAs, challenging previous assumptions about its substrate specificity.

bioRxiv · Dec 21, 2023 · PreprintBiochemistry

Targeting fungal BET bromodomains as a pan-Candida antifungal strategy

K. Wei, J. M. Overhulse, M. Arlotto, Y. Zhou, N. J. Dupper, B. A. Kashemirov, C. Garnaud, G. Bourgine, M. Cornet, G. Rabut, C. E. McKenna, C. Petosa, J. Govin

This study identifies a phenyltriazine compound that selectively targets both Bdf1 bromodomains in Candida species, showing antifungal activity against multiple Candida strains including resistant isolates.

bioRxiv · Feb 3, 2023 · PreprintBiochemistry

Differential Histone-DNA Interactions Dictate Nucleosome Recognition of the Pioneer Transcription Factor Sox

B. Ozden, R. Boopathi, A. B. Barlas, I. N. Lone, J. Bednar, C. Petosa, S. Kale, A. Hamiche, D. Angelov, S. Dimitrov, E. Karaca

This study shows that Sox PTF recognizes nucleosomes through distinct histone-DNA interactions, with specific reading mechanisms at different superhelical locations.

bioRxiv · Dec 7, 2021 · PreprintBiophysics

Binding stoichiometry and structural model of the HIV-1 Rev/Importin beta complex

D. Spittler, R.-L. Indorato, E. Boeri Erba, E. Delaforge, L. Signor, S. J. Harris, I. Garcia Saez, A. PALENCIA, F. Gabel, M. Blackledge, M. Noirclerc-Savoye, C. Petosa

This study determines the binding stoichiometry and structural model of the HIV-1 Rev/Importin beta complex using biochemical and biophysical methods.

bioRxiv · Nov 16, 2021 · PreprintBiochemistry