Spatially localized ligand binding to receptors affects magnitude and timing of signaling response
Nicholas Duong, Sahar A Kamil, Jayde Casimir-Powell, Costin N. Antonescu, Aidan I. Brown
The paper models how spatially localized ligand binding to receptors affects signaling response consistency, ligand requirements, and response timing compared to uniform binding.
bioRxiv · Jun 24, 2026 · PreprintBiophysics