TRIM7 restricts Coxsackievirus and norovirus infection by detecting the C-terminalglutamine generated by 3C protease processing
J. Luptak, D. Mallery, A. S. Jahun, A. Albecka, D. Clift, O. Ather, G. Slodkowicz, I. Goodfellow, L. James
The paper identifies TRIM7 as a viral restriction factor that recognizes a conserved C-terminal glutamine motif generated by viral proteases, inhibiting Coxsackie and norovirus replication.
bioRxiv · Jun 28, 2022Biochemistry