Author

A. Albecka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

D. Mallery· 2 shared J. Luptak· 2 shared L. C. James· 2 shared A. Gonzalez Llamazares· 1 shared A. Kipar· 1 shared A. Owen· 1 shared A. P. Carter· 1 shared A. R. Aricescu· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

D. Mallery

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

TRIM7 restricts Coxsackievirus and norovirus infection by detecting the C-terminalglutamine generated by 3C protease processing

J. Luptak, D. Mallery, A. S. Jahun, A. Albecka, D. Clift, O. Ather, G. Slodkowicz, I. Goodfellow, L. James

The paper identifies TRIM7 as a viral restriction factor that recognizes a conserved C-terminal glutamine motif generated by viral proteases, inhibiting Coxsackie and norovirus replication.

bioRxiv · Jun 28, 2022Biochemistry

Single-dose immunisation with a multimerised SARS-CoV-2 receptor binding domain (RBD) induces an enhanced and protective response in mice

R. Salzer, J. J. Clark, M. Vaysburd, V. T. Chang, A. Albecka, L. Kiss, P. Sharma, A. Gonzalez Llamazares, A. Kipar, J. A. Hiscox, A. Owen, A. R. Aricescu, J. P. Stewart, L. C. James, J. Lowe

This paper demonstrates that a multimerised SARS-CoV-2 RBD vaccine using a stable scaffold provides enhanced antibody responses and complete protection in mice.

bioRxiv · May 18, 2021Immunology

Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion

G. Papa, D. Mallery, A. Albecka, L. Welch, J. Cattin-Ortola, J. Luptak, D. Paul, H. T. McMahon, I. G. Goodfellow, A. P. Carter, S. Munro, L. C. James

bioRxiv · Aug 13, 2020Microbiology

Periphilin self-association underpins epigenetic silencing by the HUSH complex

D. M. Prigozhin, A. Albecka, C. H. Douse, I. A. Tchasovnikarova, R. T. Timms, L. E. Farleigh, S.-i. Oda, S. M. Freund, S. Maslen, P. J. Lehner, Y. Modis

This study identifies the physicochemical properties of Periphilin required for HUSH complex assembly and epigenetic silencing, showing its N-terminal domain drives aggregation and repressive mark deposition.

bioRxiv · Dec 18, 2019Biochemistry