Author

O. Crook

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:Bayesian inference· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Deane· 2 shared C.-w. Chung· 2 shared N. Gittens· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersBiochemistry

C. Deane

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2 papers

Recent·Most cited

Inferring residue level hydrogen deuterium exchange with ReX

O. Crook, N. Gittens, C.-w. Chung, C. Deane

ReX infers residue-level hydrogen deuterium exchange from HDX-MS data, showing improved performance in predicting unseen data and quantifying conformational changes in proteins.

bioRxiv · Apr 12, 2024 · PreprintBiochemistry

A functional Bayesian model for hydrogen-deuterium exchange mass-spectrometry

O. Crook, C.-w. Chung, C. Deane

The paper introduces a Bayesian framework for analyzing HDX-MS data to improve uncertainty quantification and model selection in protein conformational studies.

bioRxiv · Jul 18, 2022Biophysics