Parkinson's genes orchestrate pyroptosis through selective trafficking of mtDNA to leaky lysosomes
M. Nguyen, J. J. Collier, O. Ignatenko, G. Morin, S. Huang, M. Desjardins, H. M. McBride
The paper identifies a pyroptotic pathway involving Parkinson's disease proteins and mtDNA trafficking to lysosomes.
bioRxiv · Sep 11, 2023 · PreprintCell Biology