Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism.
A. Yamashita, O. Ignatenko, M. Nguyen, R. Lambert, K. Watt, C. Daneault, I. Robillard-Frayne, I. Topisirovic, C. Des Rosiers, H. M. McBride
The paper investigates the effects of LONP2 depletion on peroxisomal function and cholesterol metabolism, revealing cell-type-specific responses and implications for peroxisomal disorders.
bioRxiv · Mar 15, 2023Cell Biology