High resolution profiling of MHC-II peptide presentation capacity, by Mammalian Epitope Display, reveals SARS-CoV-2 targets for CD4 T cells and mechanisms of immune-escape
F. J. Obermair, F. Renoux, S. Heer, C. Lee, N. Cereghetti, G. Maestri, Y. Haldner, R. Wuigk, O. Iosefson, P. Patel, K. Triebel, M. Kopf, J. Swain, J. Kisielow
The paper uses a new platform to profile MHC-II peptide presentation capacity for SARS-CoV-2, revealing immune evasion mechanisms and CD4 T cell targets.
bioRxiv · Mar 2, 2021Immunology