Author

O. Leo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

F. Andris· 3 shared S. Denanglaire· 3 shared A. Azouz· 2 shared H. Hussein· 2 shared Y. Ajouaou· 2 shared A. Lepez· 1 shared A. Taquin· 1 shared D. Perez-Morga· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

F. Andris

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The oxygen sensor Prolyl hydroxylase domain 2 regulates the in vivo suppressive capacity of regulatory T cells

Y. Ajouaou, A. Azouz, A. Taquin, S. Denanglaire, H. Hussein, M. Krayem, F. Andris, M. Moser, S. Goriely, O. Leo

This study shows that PHD2 deficiency in regulatory T cells leads to systemic inflammation and impaired control of inflammatory responses, with the PHD2-HIF2 axis playing a key role.

bioRxiv · Mar 23, 2021Immunology

Long-term T cell fitness and proliferation is driven by AMPK-dependent regulation of oxygen reactive species

A. Lepez, T. Pirnay, S. Denanglaire, D. Perez-Morga, M. Vermeersch, O. Leo, F. Andris

This study shows AMPK is required for long-term T cell proliferation and survival by regulating reactive oxygen species.

bioRxiv · Mar 6, 2020Immunology

Multiple environmental signaling pathways control the differentiation of RORγt-expressing regulatory T cells

H. Hussein, S. Denanglaire, F. Van Gool, A. Azouz, Y. Ajouaou, H. El-Khatib, G. Oldenhove, O. Leo, F. Andris

This study identifies multiple environmental signaling pathways that regulate RORγt+ Treg differentiation, showing both positive and negative signals interact with c-Maf.

bioRxiv · Oct 8, 2019Immunology