Author

O. Stehling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

A. J. Pierik· 1 shared A. Nist· 1 shared B. Wilke· 1 shared C. Borgel· 1 shared C. M. Blinn· 1 shared F. Spantgar· 1 shared H. Swoboda· 1 shared H.-R. Chung· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. J. Pierik

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Author profile →

2 papers

Recent·Most cited

Requirements for the Biogenesis of Proteinsin the Human and Yeast Cytosol

J. J. Braymer, O. Stehling, M. Stuempfig, R. Roesser, F. Spantgar, C. M. Blinn, U. Muehlenhoff, A. J. Pierik, R. Lill

This study identifies the molecular requirements for cytosolic [2Fe-2S] protein maturation in human and yeast, showing it depends on mitochondrial ISC machinery, Atm1/ABCB7, and GSH but not CIA or cGrxs.

Proceedings of the National Academy of Sciences · May 14, 2024Peer-reviewedBiochemistry

Haptoglobin buffers lipopolysaccharides to safeguard against aberrant NFκB activation

L. Zein, J. Grossmann, H. Swoboda, C. Borgel, B. Wilke, S. Awe, A. Nist, T. Stiewe, O. Stehling, S.-A. Freibert, T. Adhikary, H.-R. Chung

This study shows haptoglobin binds and buffers lipopolysaccharides to delay NFκB activation in macrophages, suggesting its role in preventing aberrant inflammation.

bioRxiv · Nov 22, 2022 · PreprintImmunology