Author

S.-A. Freibert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Nist· 1 shared B. J. Murphy· 1 shared B. Wilke· 1 shared C. Borgel· 1 shared H. Swoboda· 1 shared H.-R. Chung· 1 shared J. Grossmann· 1 shared L. Zein· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. Nist

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Structural evidence for two-stage binding of mitochondrial ferredoxin 2 to the core iron-sulfur cluster assembly complex

R. Steinhilper, S.-A. Freibert, S. Kaltwasser, R. Lill, B. J. Murphy

The paper presents cryo-EM structures of the FDX2-bound core ISC complex, revealing two-stage binding of FDX2 and its role in electron transfer during [2Fe-2S] cluster biosynthesis.

bioRxiv · Feb 19, 2024Biophysics

Haptoglobin buffers lipopolysaccharides to safeguard against aberrant NFκB activation

L. Zein, J. Grossmann, H. Swoboda, C. Borgel, B. Wilke, S. Awe, A. Nist, T. Stiewe, O. Stehling, S.-A. Freibert, T. Adhikary, H.-R. Chung

This study shows haptoglobin binds and buffers lipopolysaccharides to delay NFκB activation in macrophages, suggesting its role in preventing aberrant inflammation.

bioRxiv · Nov 22, 2022 · PreprintImmunology