Author

P. A. Malec

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. B. Dumbrepatil· 1 shared A. M. Patel· 1 shared E. N. G. Marsh· 1 shared J. D. Hoff· 1 shared K. Zegalia· 1 shared R. T. Kennedy· 1 shared S. Ghosh· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. B. Dumbrepatil

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1 paper

Recent·Most cited

Interactions between Viperin, IRAK1 and TRAF6 couple innate immune signaling to antiviral ribonucleotide synthesis

A. B. Dumbrepatil, S. Ghosh, A. M. Patel, P. A. Malec, K. Zegalia, J. D. Hoff, R. T. Kennedy, E. N. G. Marsh

This study shows that Viperin, IRAK1, and TRAF6 interact to link innate immune signaling with antiviral ddhCTP synthesis through ubiquitination and enzymatic activation.

bioRxiv · Jan 11, 2019 · PreprintBiochemistry