The base-editing enzyme APOBEC3A catalyzes cytosine deamination in RNA with low proficiency and high selectivity
A. Barka, K. N. Berrios, P. Bailer, E. K. Schutsky, T. Wang, R. M. Kohli
This study investigates how APOBEC3A preferentially targets DNA over RNA by analyzing substrate selectivity and deamination efficiency.
bioRxiv · Nov 26, 2021Biochemistry