Disrupting the leukemia niche in the central nervous system attenuates leukemia chemoresistance
L. M. Jonart, M. Ebadi, P. Basile, K. Johnson, J. Makori, P. M. Gordon
This study shows that disrupting the meningeal niche reduces leukemia chemoresistance in the CNS by inhibiting leukemia-meningeal adhesion and enhancing drug efficacy.
bioRxiv · Sep 5, 2019Cancer Biology