Comprehensive epitope mutational scan database enables accurate T cell receptor cross-reactivity prediction
A. Banerjee, D. J. Pattinson, C. L. Wincek, P. Bunk, A. Axhemi, S. R. Chapin, S. Navlakha, H. V. Meyer
The paper introduces a database of TCR-peptide mutational assays and a Bayesian model to predict TCR cross-reactivity, showing improved performance over existing methods.
bioRxiv · Jan 22, 2024 · PreprintImmunology