Semi-analytical dynamic modeling of DNA surface-hybridization via AC Electro-kinetic steering
P. Capaldo, S. Dal Zilio, V. Torre, Y. Yang
The paper develops and validates a semi-analytical model for DNA hybridization using AC electro-kinetic steering, showing that detection limit and specificity depend on probe/target binding affinity, SAM density, and interfacial electric field.
bioRxiv · Feb 25, 2020 · PreprintBiophysics