Unlocking Predictive Power: A Machine Learning Tool Derived from In-Depth Analysis to Forecast the Impact of Missense Variants in Human Filamin C
M. Nagy, G. Mlynek, J. Kostan, L. Smith, D. Puehringe, P. Charron, T. B. Rasmussen, Z. Bilinska, M. M. Akhtar, P. Syrris, L. R. Lopes, P. M. Elliott, M. Gautel, O. Carugo, K. Djinovic-Carugo
The paper develops a machine learning model to predict the impact of missense variants in human filamin C, achieving high accuracy in distinguishing pathogenic from non-pathogenic variants.
bioRxiv · Aug 5, 2023 · PreprintBiophysics