In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury.
S. Giannakopoulos, D. P. Strange, B. Jiyarom, O. Abdelaal, A. W. Bradshaw, V. R. Nerurkar, M. A. Ward, J. Bakse, J. Yap, S. Vanapruks, W. Boisvert, M. Tallquist, C. Shikuma, H. Sadri-Ardekani, P. Clapp, , S. Verma
This study shows SARS-CoV-2 does not directly infect human testicular cells but causes injury through bystander effects from systemic inflammation or viral antigens.
bioRxiv · Sep 21, 2022 · PreprintMicrobiology