Heparan sulfate structure is influenced by the ER-Golgi dynamics of its modifying enzymes
M. Meneghetti, P. Deboni, C. Palomino, L. Braga, R. Cavalheiro, G. Viana, E. Yates, H. Nader, M. Lima
This study shows that changes in the localization of HS-modifying enzymes in the ER-Golgi pathway influence HS structure, highlighting the role of vesicular trafficking in HS biosynthesis.
bioRxiv · Jan 23, 2020 · PreprintCell Biology