Author

H. Nader

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

E. Yates· 2 shared M. Lima· 2 shared M. Meneghetti· 2 shared A. Bisio· 1 shared C. Mycroft-West· 1 shared C. Palomino· 1 shared D. Fernig· 1 shared D. Su· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiochemistry

E. Yates

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2 papers

Recent·Most cited

Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the surface protein (spike) S1 receptor binding domain with heparin.

C. Mycroft-West, D. Su, I. Pagani, T. Rudd, S. Elli, S. Guimond, G. Miller, M. Meneghetti, H. Nader, Y. Li, Q. Nunes, P. Procter, N. Mancini, M. Clementi, A. Bisio, , M. A. Skidmore

This study shows heparin inhibits SARS-CoV-2 invasion by binding to the Spike protein's RBD and inducing conformational changes, with structural features of heparin playing a key role.

bioRxiv · Apr 28, 2020Biochemistry

Heparan sulfate structure is influenced by the ER-Golgi dynamics of its modifying enzymes

M. Meneghetti, P. Deboni, C. Palomino, L. Braga, R. Cavalheiro, G. Viana, E. Yates, H. Nader, M. Lima

This study shows that changes in the localization of HS-modifying enzymes in the ER-Golgi pathway influence HS structure, highlighting the role of vesicular trafficking in HS biosynthesis.

bioRxiv · Jan 23, 2020 · PreprintCell Biology