Combinatorial CAR design improves target restriction
H. Köksal, P. Dillard, A. Juzeniene, G. Kvalheim, E. B. Smeland, J. H. Myklebust, E. M. Inderberg, S. Walchli
This study designs combinatorial CAR constructs to improve target selectivity and efficacy in B-cell malignancies while reducing off-target effects.
bioRxiv · Oct 9, 2020Immunology