Large-scale statistical mapping of T-cell receptor β sequences to Human Leukocyte Antigens
H. J. Zahid, R. Taniguchi, P. Ebert, I.-T. Chow, C. Gooley, J. Lv, L. Pisani, M. Rusnak, R. Elyanow, H. Takamatsu, W. Zhou, J. Greissl, H. Robins, J. M. Carlson
The paper maps T-cell receptor β sequences to specific HLA allotypes using population-level TCR repertoire data, enabling accurate HLA imputation and revealing insights into TCR-HLA interactions.
bioRxiv · Apr 1, 2024 · PreprintImmunology