The eukaryotic replisome requires an additional helicase to disarm dormant replication origins
J. Hill, P. Eickhoff, L. Drury, A. Costa, J. Diffley
The paper shows that Pif1 helicase, along with the replisome, removes unfired MCM DHs from replicating DNA, enabling efficient replication and termination.
bioRxiv · Sep 17, 2020 · PreprintBiochemistry