Uncovering the regulatory landscape of early human B-cell lymphopoiesis and its implications in the pathogenesis of B-cell acute lymphoblastic leukemia
N. Planell, X. Martinez-de-Morentin, D. Mouzo, D. Lara-Astiaso, A. Vilas-Zornoza, P. San Martin-Uriz, D. Alignani, B. Paiva, A. Maillo, A. Kurowska, N. Berastegui, P. Garcia-Olloqui, A. Urdangarin, P. Noori, A. Ortega-Legarreta, , D. Gomez-Cabrero
This study characterizes the gene regulatory network of early human B-cell development and identifies regulatory elements linked to B-cell acute lymphoblastic leukemia.
bioRxiv · Jul 1, 2023 · PreprintImmunology