Stiffening of prostate cancer cells driven by actin filaments - microtubules crosstalk confers resistance to microtubule-targeting drugs
A. Kubiak, M. Chighizola, C. Schulte, N. Bryniarska, J. Wesolowska, M. Pudelek, D. Ryszawy, A. Basta-Kaim, P. Laidler, A. Podesta, M. Lekka
This study shows that prostate cancer cells stiffen in response to microtubule-targeting drugs due to actin-microtubule crosstalk, contributing to drug resistance.
bioRxiv · Jun 14, 2020Biophysics