The propofol binding sites of prokaryotic voltage-gated sodium channels
E. C. Yang, W. Bu, A. Suma, V. Carnevale, K. Grasty, P. Loll, K. Woll, N. Bhanu, B. A. Garcia, R. G. Eckenhoff, M. Covarrubias
This study identifies conserved propofol binding sites in prokaryotic voltage-gated sodium channels and shows how conformational changes at these sites mediate propofol's effects on channel function.
bioRxiv · Oct 28, 2020 · PreprintBiophysics