Author

W. Bu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Pharmacology & Toxicology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:electrophysiology· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

R. G. Eckenhoff· 3 shared B. A. Garcia· 2 shared K. Woll· 2 shared T. T. Joseph· 2 shared A. Suma· 1 shared A. Wague· 1 shared C. M. Nimigean· 1 shared C.-J. Wei· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersPharmacology & Toxicology

R. G. Eckenhoff

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1)

T. T. Joseph, W. Bu, O. Haji-Ghassemi, Y. S. Chen, K. Woll, P. D. Allen, G. Brannigan, F. van Petegem, R. G. Eckenhoff

This study shows propofol directly binds and inhibits RyR1, reducing Ca2+ release and potentially protecting against malignant hyperthermia.

bioRxiv · Jan 10, 2024 · PreprintPharmacology & Toxicology

A bivalent EBV vaccine induces neutralizing antibodies that block B and epithelial cell infection and confer immunity in humanized mice

C.-J. Wei, W. Bu, L. A. Nguyen, J. D. Batchelor, J. Kim, S. Pittaluga, J. R. Fuller, H. Nguyen, T.-H. Chou, J. Cohen, G. J. Nabel

bioRxiv · Jan 18, 2022 · PreprintImmunology

The propofol binding sites of prokaryotic voltage-gated sodium channels

E. C. Yang, W. Bu, A. Suma, V. Carnevale, K. Grasty, P. Loll, K. Woll, N. Bhanu, B. A. Garcia, R. G. Eckenhoff, M. Covarrubias

This study identifies conserved propofol binding sites in prokaryotic voltage-gated sodium channels and shows how conformational changes at these sites mediate propofol's effects on channel function.

bioRxiv · Oct 28, 2020 · PreprintBiophysics

Mechanistic insights into volatile anesthetic modulation of K2P channels

A. Wague, T. T. Joseph, K. A. Woll, W. Bu, K. A. Vaidya, N. V. Bhanu, B. A. Garcia, C. M. Nimigean, R. G. Eckenhoff, P. M. Riegelhaupt

This study identifies a volatile anesthetic binding site in TREK1 K2P channels and shows its role in modulating channel activity through molecular dynamics and mutagenesis.

bioRxiv · Jun 10, 2020Pharmacology & Toxicology

Subphase Material Stabilizes Films of Pulmonary Surfactant

K. Andreev, M. Martynowycz, I. Kuzmenko, W. Bu, S. B. Hall, D. Gidalevitz

The paper uses X-ray scattering to show that vesicles in the subphase enhance the stability of pulmonary surfactant monolayers by increasing ordered interfacial structures.

bioRxiv · Feb 27, 2020 · PreprintBiophysics