Hypoxia modulates P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP) drug transporters in Brain Endothelial Cells of the Developing Human Blood-Brain Barrier
H. Mughis, P. Lye, G. Imperio, E. Bloise, S. G. Matthews
The paper examines how hypoxia affects P-gp and BCRP transporter expression and activity in fetal brain endothelial cells, showing differing responses in early and mid-gestation.
bioRxiv · May 24, 2023Physiology