This study identifies EZH2 as a master regulator of EMT in carcinoma cells, showing it represses mesenchymal genes and facilitates tumour colonization.

DOI 10.1101/2022.03.11.483977

humanbulk RNA-seq

Evolutionary BiologybioRxivAug 25, 2020

Deep data mining reveals variable abundance and distribution of microbial reproductive manipulators within and among diverse host species

P. Medina, S. Russell, K. Aswadhati, R. Corbett-Detig

The paper uses data mining to analyze microbial reproductive manipulators in host species, finding Wolbachia infects most arthropods and nematodes, with host species explaining significant variation in bacterial density.

DOI 10.1371/journal.pone.0288261

Drosophilametagenomics

Evolutionary BiologybioRxivDec 29, 2019

Genomic adaptations to aquatic and aerial life in mayflies and the origin of wings in insects

I. Almudi, J. Vizueta, A. de Mendoza…·F. Casares

This study analyzes the genome and gene expression of mayflies to uncover genomic adaptations related to aquatic and aerial life and the origin of wings in insects.

DOI 10.1038/s41467-020-16284-8

whole-genome sequencingbulk RNA-seq

Evolutionary BiologybioRxivJul 25, 2018

Estimating the timing of multiple admixture pulses during local ancestry inference.

P. Medina, B. Thornlow, R. Nielsen, R. Corbett-Detig

This paper introduces a method to estimate multiple admixture events using coalescent theory and applies it to Drosophila melanogaster data, finding evidence for both recent and ancient admixture pulses.

DOI 10.1534/genetics.118.301411

Drosophilastatistical model