Author

P. Melamed

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Assay:DNA methylation· 3 Approach:experimental assay· 3

Frequent Co-Authors

A. Kaplan· 3 shared H. Khamis· 3 shared S. Rudnizky· 3 shared A. Meller· 1 shared A. Squires· 1 shared E. Goren· 1 shared O. Malik· 1 shared Y. Ginosar· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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3 shared papersBiophysics

A. Kaplan

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3 papers

Recent·Most cited

Single molecule characterization of the binding kinetics of a transcription factor and its modulation by DNA sequence and methylation

H. Khamis, S. Rudnizky, P. Melamed, A. Kaplan

This paper introduces a single-molecule assay to measure transcription factor binding kinetics and shows how DNA sequence and methylation modulate these interactions.

bioRxiv · May 19, 2021Biophysics

Extended and dynamic linker histone-DNA interactions control chromatosome compaction

S. Rudnizky, H. Khamis, Y. Ginosar, E. Goren, P. Melamed, A. Kaplan

This study reveals extended and dynamic linker histone-DNA interactions that control chromatosome compaction through single-molecule unzipping experiments.

bioRxiv · Oct 10, 2020Biophysics

Single-molecule DNA unzipping reveals asymmetric modulation of a transcription factor by its binding site sequence and context

S. Rudnizky, H. Khamis, O. Malik, A. Squires, A. Meller, P. Melamed, A. Kaplan

This study uses single-molecule DNA unzipping to show how Egr-1's binding affinity and structure are modulated by its binding site sequence and flanking context, with ZF3 showing stronger effects.

bioRxiv · Nov 30, 2017Biophysics