Author

P. Mendes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Approach:deep learning· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

R. Laubenbacher· 2 shared A. Dongari-Bagtzoglou· 1 shared A. Regnier-Vigouroux· 1 shared A. Segura-Castillo· 1 shared A. Thompson· 1 shared C. Geiss· 1 shared D. B. Kell· 1 shared D. Bravo-Estupinan· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersMicrobiology

R. Laubenbacher

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Understanding Lactobacillus paracasei and Streptococcus oralis biofilm interactions through agent-based modeling

L. Archambault, S. Koshy-Chenthittayil, A. Thompson, A. Dongari-Bagtzoglou, R. Laubenbacher, P. Mendes

This paper uses agent-based modeling and experiments to study interactions between Lactobacillus paracasei and Streptococcus oralis in biofilms, finding that L. paracasei may inhibit S. oralis growth.

bioRxiv · Apr 29, 2021Microbiology

MYC dosage compensation is mediated by miRNA-transcription factor interactions in aneuploid cancer

M. S. Acon, C. Geiss, J. Torres-Calvo, D. Bravo-Estupinan, G. Oviedo, J. L. Arias-Arias, L. A. Rojas-Matey, E. Baez, G. Vasquez-Vargas, Y. Oses-Vargas, J. Guevara-Coto, A. Segura-Castillo, F. Siles-Canales, S. Quiros-Barrantes, A. Regnier-Vigouroux, , R. M. Mora-Rodriguez

This study identifies miRNA-transcription factor interactions that mediate MYC dosage compensation in aneuploid cancer, showing a negative correlation with patient survival in breast cancer.

bioRxiv · Apr 20, 2021Cancer Biology

Why most transporter mutations that cause antibiotic resistance are to efflux pumps rather than to import transporters

P. Mendes, E. Girardi, G. Superti-Furga, D. B. Kell

The paper shows that mutations increasing efflux pump activity are more effective than inhibiting uptake transporters in reducing antibiotic internal concentrations, suggesting efflux inhibition as a better strategy for combating resistance.

bioRxiv · Jan 16, 2020 · PreprintMicrobiology

An important role for periplasmic storage in Pseudomonas aeruginosa copper homeostasis revealed by a combined experimental and computational modeling study

J. H. Parmar, J. Quintana, D. Ramirez, R. Laubenbacher, J. M. Argüello, P. Mendes

The paper combines experimental and computational modeling to reveal a periplasmic copper storage mechanism in Pseudomonas aeruginosa that is critical for copper homeostasis under dyshomeostasis conditions.

bioRxiv · Jul 13, 2018Microbiology