Author

P. Mutz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Research Focus:cell type annotation· 3 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:metagenomics· 2 Research Focus:phylogenetics / evolution· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

E. V. Koonin· 6 shared Y. I. Wolf· 4 shared G. Faure· 3 shared M. Krupovic· 3 shared N. Yutin· 3 shared F. Zhang· 2 shared N. D. Rochman· 2 shared A. E. Gorbalenya· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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6 shared papersMicrobiology

E. V. Koonin

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Jumping DNA polymerases in bacteriophages

N. Yutin, P. Mutz, Y. I. Wolf, M. Krupovic, E. V. Koonin

The paper identifies instances of DNA polymerase (DNAP) swapping among bacteriophages, showing gene replacements between families and subfamilies without altering surrounding gene organization.

bioRxiv · Apr 26, 2024 · PreprintMicrobiology

Mriyaviruses: Small Relatives of Giant Viruses

N. Yutin, P. Mutz, M. Krupovic, E. V. Koonin

The paper identifies a new class of viruses, Mriyaviricetes, with small genomes related to giant Nucleocytoviricota viruses, suggesting they are close relatives of their ancestors and use a unique rolling circle replication mechanism.

bioRxiv · Feb 29, 2024Microbiology

Exaptation of inactivated host enzymes for structural roles in orthopoxviruses and novel protein folds revealed by protein structure modeling

P. Mutz, W. Resch, G. Faure, T. G. Senkevich, E. V. Koonin, B. Moss

The paper uses AlphaFold2 to predict structures of orthopoxvirus proteins, revealing exaptation of inactivated host enzymes for structural roles and novel protein folds.

bioRxiv · Nov 22, 2022 · PreprintMicrobiology

Varidnaviruses in the human gut: a major expansion of the order Vinavirales

N. Yutin, M. Rayko, D. Antipov, P. Mutz, Y. I. Wolf, M. Krupovic, E. V. Koonin

This study identifies and characterizes varidnaviruses in the human gut virome, revealing their prevalence as prophages and suggesting limited active infections.

bioRxiv · Jul 18, 2022Microbiology

Human pathogenic RNA viruses establish non-competing lineages by occupying independent niches

P. Mutz, N. D. Rochman, Y. I. Wolf, G. Faure, F. Zhang, E. V. Koonin

This study analyzes 27 human pathogenic RNA viruses to show they form multiple co-circulating lineages with low turnover rates, occupying non-competing epidemiological niches.

bioRxiv · Dec 10, 2021 · PreprintEvolutionary Biology

Deep mining of the Sequence Read Archive reveals bipartite coronavirus genomes and inter-family Spike glycoprotein recombination

C. Lauber, J. Vaas, F. Klingler, P. Mutz, A. E. Gorbalenya, R. Bartenschlager, S. Seitz

The paper analyzes Sequence Read Archive data to discover novel nidoviruses, including fish coronaviruses with bipartite genomes and inter-family Spike recombination.

bioRxiv · Oct 20, 2021Microbiology

Ongoing Global and Regional Adaptive Evolution of SARS-CoV-2

N. D. Rochman, Y. I. Wolf, G. Faure, P. Mutz, F. Zhang, E. V. Koonin

This study analyzes 300,000 SARS-CoV-2 genomes to show ongoing adaptive evolution, with positive selection in spike and nucleocapsid proteins and regional diversification over time.

bioRxiv · Oct 12, 2020Microbiology