Author

G. Faure

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Approach:statistical model· 3 Approach:deep learning· 2 Assay:whole-genome sequencing· 2 Approach:machine learning (classical)· 1 Research Focus:phylogenetics / evolution· 1 Assay:protein structure· 1

Frequent Co-Authors

E. V. Koonin· 5 shared F. Zhang· 4 shared Y. I. Wolf· 4 shared N. D. Rochman· 3 shared P. Mutz· 3 shared A. B. Gussow· 1 shared B. Moss· 1 shared N. Auslander· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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5 shared papersMicrobiology

E. V. Koonin

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Exaptation of inactivated host enzymes for structural roles in orthopoxviruses and novel protein folds revealed by protein structure modeling

P. Mutz, W. Resch, G. Faure, T. G. Senkevich, E. V. Koonin, B. Moss

The paper uses AlphaFold2 to predict structures of orthopoxvirus proteins, revealing exaptation of inactivated host enzymes for structural roles and novel protein folds.

bioRxiv · Nov 22, 2022 · PreprintMicrobiology

Human pathogenic RNA viruses establish non-competing lineages by occupying independent niches

P. Mutz, N. D. Rochman, Y. I. Wolf, G. Faure, F. Zhang, E. V. Koonin

This study analyzes 27 human pathogenic RNA viruses to show they form multiple co-circulating lineages with low turnover rates, occupying non-competing epidemiological niches.

bioRxiv · Dec 10, 2021 · PreprintEvolutionary Biology

Epistasis at the SARS-CoV-2 RBD Interface and the Propitiously Boring Implications for Vaccine Escape

N. D. Rochman, G. Faure, Y. I. Wolf, P. Freddolino, F. Zhang, E. V. Koonin

This study analyzes epistatic interactions among RBD mutations in SARS-CoV-2 variants to assess their impact on vaccine escape potential.

bioRxiv · Aug 30, 2021 · PreprintMicrobiology

Ongoing Global and Regional Adaptive Evolution of SARS-CoV-2

N. D. Rochman, Y. I. Wolf, G. Faure, P. Mutz, F. Zhang, E. V. Koonin

This study analyzes 300,000 SARS-CoV-2 genomes to show ongoing adaptive evolution, with positive selection in spike and nucleocapsid proteins and regional diversification over time.

bioRxiv · Oct 12, 2020Microbiology

Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses

N. Auslander, A. B. Gussow, G. Faure, Y. I. Wolf, F. Zhang, E. V. Koonin

This study identifies genomic features distinguishing highly pathogenic SARS-CoV-2, SARS-CoV, and MERS-CoV from less pathogenic coronaviruses using comparative genomics and machine learning.

bioRxiv · Apr 5, 2020Microbiology