Peroxidasin is associated with a mesenchymal-like transcriptional phenotype and promotes invasion in metastatic melanoma
C. C. Smith-Diaz, A. Kumar, A. Das, P. Pace, K. Chitcholtan, N. J. Magon, S. H. M. Hossain, M. R. Eccles, C. C. Winterbourn, M. Paumann-Page
This study shows that peroxidasin (PXDN) promotes invasion in metastatic melanoma by supporting a mesenchymal-like transcriptional phenotype, as demonstrated through transcriptomic and proteomic analyses.
bioRxiv · Apr 5, 2024Cancer Biology