Author

P. Pfaff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Mac Sweeney· 1 shared C. Joesch· 1 shared C. Lotz-Jenne· 1 shared G. Bourquin· 1 shared L. Goglia· 1 shared M. Mueller· 1 shared M. Wicki· 1 shared N. Artico· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Mac Sweeney

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1 paper

Recent·Most cited

Discovery and binding mode of small molecule inhibitors of the apo form of human TDO2

C. Lotz-Jenne, R. Lange, S. Cren, G. Bourquin, L. Goglia, T. Kimmerlin, M. Wicki, M. Mueller, N. Artico, S. Ackerknecht, P. Pfaff, C. Joesch, A. Mac Sweeney

This study identifies small molecule inhibitors that bind to apo-TDO2 and inhibits its activity at low nanomolar concentrations, along with their co-crystal structures.

bioRxiv · Jan 9, 2024Biochemistry