BiochemistryScientific ReportsPeer-reviewed
Discovery and binding mode of small molecule inhibitors of the apo form of human TDO2
C. Lotz-Jenne, R. Lange, S. Cren…·A. Mac Sweeney
This study identifies small molecule inhibitors that bind to apo-TDO2 and inhibits its activity at low nanomolar concentrations, along with their co-crystal structures.
DOI 10.1038/s41598-024-78981-4