RNAs undergo phase transitions with lower critical solution temperatures
G. M. Wadsworth, W. J. Zahurancik, X. Zeng, P. Pullara, L. B. Lai, V. Sidharthan, R. V. Pappu, V. Gopalan, P. R. Banerjee
The paper shows RNAs undergo phase transitions with lower critical solution temperatures, driven by Mg2+ and phosphate backbone interactions, and can suppress RNase P activity.
bioRxiv · Oct 17, 2022Biophysics