Multi-omics data integration reveals molecular mechanisms of carfilzomib resistance in multiple myeloma
A. Malyutina, P. Sergeev, J. Huber, J. J. Miettinen, A. Bolomsky, J. Bao, A. O. Parsons, A. Mueller, N. Marella, M. van Duin, H. Ludwig, J. Tang, C. A. Heckman
This study identifies molecular mechanisms of carfilzomib resistance in multiple myeloma using multi-omics data from cell lines and patient samples, revealing potential drug combinations to overcome resistance.
bioRxiv · May 26, 2024 · PreprintCancer Biology