Kinesin-2 from C. reinhardtii is an atypically fast and auto-inhibited motor that is activated by heterotrimerization for intraflagellar transport
P. Sonar, W. Youyen, A. Cleetus, P. Wisanpitayakorn, I. S. Mousavi, W. L. Stepp, W. O. Hancock, E. Tuezel, Z. Oekten
This study investigates the function of kinesin-2 motors in C. reinhardtii, showing that FLA8/10 is auto-inhibited and activated by KAP subunit heterotrimerization for fast intraflagellar transport.
bioRxiv · Nov 26, 2019Biophysics