Author

W. L. Stepp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Assay:fluorescence / live-cell microscopy· 2 Approach:microscopy & imaging analysis· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

S. Manley· 2 shared A. Cleetus· 1 shared A. Habel· 1 shared C. Zhang· 1 shared D. K. Newman· 1 shared D. Mahecic· 1 shared E. Tuezel· 1 shared I. S. Mousavi· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiophysics

S. Manley

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Polyphosphate affects cytoplasmic and chromosomal dynamics in nitrogen-starved Pseudomonas aeruginosa

S. Magkiriadou, A. Habel, W. L. Stepp, D. K. Newman, S. Manley, L. R. Racki

This study shows that polyphosphate reduces cytoplasmic mobility and chromosomal accessibility in nitrogen-starved Pseudomonas aeruginosa, potentially explaining its pleiotropic effects.

bioRxiv · Dec 23, 2021Biophysics

Event-driven acquisition for content-enriched microscopy

D. Mahecic, W. L. Stepp, C. Zhang, J. Griffie, M. Weigert, S. Manley

The paper introduces an event-driven acquisition framework that enhances microscopy by capturing dynamic biological events with optimized imaging rates.

bioRxiv · Oct 4, 2021Cell Biology

Kinesin-2 from C. reinhardtii is an atypically fast and auto-inhibited motor that is activated by heterotrimerization for intraflagellar transport

P. Sonar, W. Youyen, A. Cleetus, P. Wisanpitayakorn, I. S. Mousavi, W. L. Stepp, W. O. Hancock, E. Tuezel, Z. Oekten

This study investigates the function of kinesin-2 motors in C. reinhardtii, showing that FLA8/10 is auto-inhibited and activated by KAP subunit heterotrimerization for fast intraflagellar transport.

bioRxiv · Nov 26, 2019Biophysics

Resolving kinesin stepping: one head at a time

W. L. Stepp, Z. Ökten

This study uses dual-color super resolution microscopy to show that the tail domain of kinesin-2 selectively inhibits one head during processive stepping, revealing a mechanism of autoinhibition.

Life Science Alliance · Oct 10, 2019Peer-reviewedBiophysics