How to navigate the myosin-V motor through the actin network
P. Spieler, A. Oberhofer, D. Zimmermann, E. Brames, A. N. Hume, Z. Oekten
This paper shows that phosphorylation regulates myosin-Va switching behavior at actin-actin crossings via its adaptor protein Mlph, enabling precise cargo navigation in amphibians but not in zebrafish.
bioRxiv · Mar 11, 2020 · PreprintBiochemistry