Role of the circadian clock "Death-Loop" in the DNA damage response underpinning cancer treatment resistance
N. M. Vainshelbaum, K. Salmina, B. I. Gerashchenko, M. Lazovska, P. Zayakin, M. S. Cragg, D. Pjanova, J. Erenpreisa
The paper investigates how the circadian clock 'death-loop' contributes to cancer treatment resistance by enabling DNA damage tolerance and telomere renewal in polyploid cancer cells.
bioRxiv · Jan 14, 2022Cancer Biology