Cancer BiologybioRxiv
Role of the circadian clock "Death-Loop" in the DNA damage response underpinning cancer treatment resistance
N. M. Vainshelbaum, K. Salmina, B. I. Gerashchenko…·J. Erenpreisa
The paper investigates how the circadian clock 'death-loop' contributes to cancer treatment resistance by enabling DNA damage tolerance and telomere renewal in polyploid cancer cells.
DOI 10.3390/cells11050880