Protein Collapse is Encoded in the Folded State Architecture
H. S. Samanta, P. Zhuravlev, M. Hinczewski, N. Hori, S. Chakrabarti, D. Thirumalai
The paper develops a polymer physics-based theory to assess protein collapsibility using contact maps, showing that beta-sheet proteins are more collapsible than alpha-helical ones and explaining the origin of multi-domain proteins.
Soft Matter · Jan 1, 2017Peer-reviewedBiophysics