Author

Patrick Parker

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Dwight E. BerglesiD· 3 shared Aileen QiiD· 1 shared Alexei M. BygraveiD· 1 shared Ben LangmeadiD· 1 shared Benjamin G. Dubner· 1 shared Clayton P. SantiagoiD· 1 shared David A. BakeriD· 1 shared Dingchang LiniD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersNeuroscience

Dwight E. BerglesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Conservation of neuron-astrocyte coordinated activity among sensory processing centers of the developing brain

Vered Kellner, Patrick Parker, Dongeun Heo, Xuelong Mi, Mikhail Coen, Guoqiang Yu, Gesine Saher, Loyal A. Goff, Dwight E. Bergles

The paper shows that retinal ganglion cell activity induces correlated astrocyte calcium waves in the superior colliculus, dependent on mGluR5 and mGluR3, suggesting a conserved mechanism across sensory systems.

Glia · Mar 26, 2026Peer-reviewedNeuroscience

Genetically encoded assembly recorder temporally resolves cellular histories in cellulo and in vivo

Yuqing Yan, Jiaxi Lu, Zhe Li, Zuohan Zhao, Timothy F. Shay, Shunzhi Wang, Yaping Lei, Yimei Wang, Wei Chen (23863), Patrick Parker, Hongru Yang, Aileen Qi, Yongzhi Sun, Dwight E. Bergles, David A. Baker, Dingchang Lin

This paper introduces GEMINI, a tool that records cellular activity histories with high temporal resolution, and demonstrates its application in tracking transcriptional changes and inflammation dynamics in vivo.

Nature · Mar 3, 2026Peer-reviewedBioengineering

Cell-specific regulation of gene expression using splicing-dependent frameshifting.

Jonathan P. Ling, Alexei M. Bygrave, Clayton P. Santiago, Rogger P. Carmen‐Orozco, Vickie Trinh, Minzhong Yu, Yini Li, Ying Liu, Kyra D. Bowden, Leighton H. Duncan, Jeong Soon Han, Kamil Taneja, Rochinelle Dongmo, Travis A. Babola, Patrick Parker, , Seth Blackshaw

This paper introduces SLED, a splicing-based method to control gene expression in specific cell types, demonstrating its utility in targeting neurons, photoreceptors, and cancer cells.

Nature Communications · Oct 1, 2022Peer-reviewedMolecular Biology