Peter Gerges

BLIMP1 shapes germinal center B cell clonal diversity by gating chromatin accessibility during light-to-dark zone transition

This study shows Blimp1 restricts clonal dominance in germinal center B cells by controlling chromatin accessibility and BCR signaling during the light-to-dark zone transition.

Expanding the DNA Motif Lexicon of the Transcriptional Regulatory Code

The paper expands the DNA motif lexicon of transcriptional regulatory code by identifying composite elements and using a deep learning model to predict their activity and impact of variants.

Multi-scale gene regulatory networks for resolving transcription factor and autoimmune variant impacts on human B cell fate dynamics

Altered AP-1, RUNX, and EGR chromatin dynamics drive fibrotic lung disease

The paper identifies transcription factor networks driving fibrotic lung disease using multiomic single-cell data from SSc-ILD and control lungs.