Altered AP-1, RUNX, and EGR chromatin dynamics drive fibrotic lung disease
Eleanor Valenzi, Minxue Jia, Peter Gerges, Jing‐Yu Fan, Tracy Tabib, Rithika Behara, Yuechen Zhou, John Sembrat, Jishnu Das, Panayiotis V. Benos, Harinder Singh, Robert Lafyatis
The paper identifies transcription factor networks driving fibrotic lung disease using multiomic single-cell data from SSc-ILD and control lungs.
bioRxiv · Oct 23, 2024 · PreprintSystems Biology