Metabolomic Network Analysis Reveals Reorganization of Lipid and Steroid Programs Linked to Right Ventricular-Pulmonary Vascular Function in Pulmonary Hypertension
Ivor Clinton, Julie C. Coursen, Darin T. Rosen, Karthik S. Suresh, Aparna Balasubramanian, Todd M. Kolb, Rachel L. Damico, Stephen C. Mathai, Steven Hsu, Monica Mukherjee, Jose Emanuel Finet, Gabriele Grünig, John Barnard, Anna Ryan Hemnes, Jane A. Leopold, , PVDOMICS Study Group
The paper identifies metabolic modules in PAH patients linked to RV-PV function using WGCNA and validates findings in independent cohorts.
bioRxiv · Jun 22, 2026 · PreprintPhysiology