Author
Johns Hopkins UniversityORCID 0000-0003-2920-0949Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
J. Richard Brewer, Ailin Han, Amin H. Nassar…·Richard Anthony Flavell
The paper identifies DPP9 as a genetic susceptibility gene for checkpoint inhibitor pneumonitis and shows IL-18 blockade could be a therapeutic strategy.
Ivor Clinton, Julie C. Coursen, Darin T. Rosen…·PVDOMICS Study Group
The paper identifies metabolic modules in PAH patients linked to RV-PV function using WGCNA and validates findings in independent cohorts.
Stuti Agarwal, Anuradha Bankar, Lyong Heo…·Vinicio de Jesús Pérez
This study identifies CES1 deficiency as a driver of metabolic reprogramming and endothelial dysfunction in pulmonary arterial hypertension, showing its role in lipid metabolism and oxidative stress.
Manuella Ribas Andrade, Xin Yun, Michael P. Croglio…·Larissa A. Shimoda
This study shows NHE1 promotes apoptosis resistance in PASMCs from PH models through p38 suppression, independent of ion transport or ezrin-binding.
Tijana Tuhy, Julie C. Coursen, Tammy Graves…·Catherine E. Simpson
This study uses single-cell RNA sequencing to compare scleroderma-associated and idiopathic pulmonary arterial hypertension, identifying distinct pathobiological features and potential drug targets.
Xin Yun, Shannon E. Niedermeyer, Manuella Ribas Andrade…·Larissa A. Shimoda
Shannon E. Niedermeyer, Xin Yun, Marielena Trujillo…·Larissa A. Shimoda
The paper identifies a novel interaction between aquaporin-1 and caspase-3 in PASMCs, showing AQP1 levels correlate with caspase-3 activity.