Rewiring native post-transcriptional carbon regulators to build multi-layered genetic circuits and optimize engineered microbes for bioproduction
T. R. Simmons, G. Partipilo, A. C. Stankes, R. Srivastava, R. Buchser, D. Chiu, B. K. Keitz, L. M. Contreras
This paper rewires the Csr Network in E. coli to create tunable genetic circuits for post-transcriptional control, achieving three-fold increased mevalonate production.
bioRxiv · Oct 4, 2023 · PreprintBioengineering